To address study limitations, two meta-analyses of schizophrenic link were performed,96, 97 and achieved some overlapping results. Badner and Gershon96 relied on published data, analyzed using different methods, and found support for the existence of susceptibility genes on chromosomes 8p, 13q and 22q for schizophrenia. On the other hand, Lewis et al.97 applied genome-based meta-analysis, which consists of data collected using identical methods in many published and unpublished and preferred 2q studies. Several loci appeared: 5q, 3p, 11q, 6p, 1q, 22q, 8p, 20q and 14p (in descending order of meaning). Regions 8p and 22q were supported by both meta-analyses. In addition to well-replicated Loci, chromosomal regions did not achieve full confirmation of the positive link with the disease, such as 3p, 11q, 14p and 20q. Nanko S, Kunugi H, Sasaki T, Fukuda R, Kawate T, Kazamatsuri H. The perizentrial region of chromosome 9 is a potential candidate region for the binding study of schizophrenia. Biol Psychiatry 1993; 33 : 655-658. OligoFISH®Spers probes made with 100% analytical specificity and >98% analytical sensitivity (Table 1), in accordance with what the probes are supposed to offer as a rapid test, which targets only certain parts of the chromosome and exceeds the recommendations of the American College of Genetic Medicine27 as well as most traditional FISH probes.
Figure 1 shows the correct position of the two OligoFISH ® fields. Despite decades of surveillance, research and public relations, prostate cancer screening remains a major public health priority and an ongoing debate. Urologists and other health groups agree that epidemiological, clinical and economic data support the need for more effective, non-invasive or minimally invasive screening and diagnostic approaches.8.12 This study showed that OligoFISH® has the appropriate level of reproducible specificity and sensitivity necessary for accurate early diagnosis of prostate cancer by minimally invasive methods. The collection of prostate cells in the urine, collected with pressure after DRE, significantly increased the harvest of the prostate cell, which allowed sufficient cell accumulation to test the oligoFISH®Panelson. The proportion of prostate cells found in the urine samples tested ranged from 40% to 83% depending on DRE under pressure. This allowed the collection of a sufficient number of high-quality prostate cells to perform the test….